Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells

The Journal of physiology

Certain essential cognitive processes require the precise temporal interplay between glutamatergic (excitatory) pyramidal cells and γ-aminobutyric acid (GABA)-releasing inhibitory interneurons in the hippocampus. Basket cells, the main class of interneurons, target pyramidal cell somata and proximal dendrites and thus are poised to modify network oscillations. Though only present in limited numbers, the impaired development of basket cells can result in changes in the hippocampal circuitry…

Released at: 22.09.2020, written by webmaster_popp