Neonatal handling increases sensitivity to acute neurodegeneration in adult rats

Journal of neurobiology

Environmental stimuli during the perinatal period can result in persistent individual differences in neural viability and cognitive functions. Earlier studies have shown that brief daily maternal separation and/or handling of rat pups during the first weeks of life reduces stress reactivity during adulthood and attenuates neuronal loss and cognitive decline during aging. In the present study we examined whether neonatal handling also affects the sensitivity of the adult brain to an acute…

Released at: 23.09.2020, written by webmaster_popp

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