Life-long epigenetic programming of cortical architecture by maternal ‚Western‘ diet during pregnancy

Molecular psychiatry

The evolution of human diets led to preferences toward polyunsaturated fatty acid (PUFA) content with ‚Western‘ diets enriched in ω-6 PUFAs. Mounting evidence points to ω-6 PUFA excess limiting metabolic and cognitive processes that define longevity in humans. When chosen during pregnancy, ω-6 PUFA-enriched ‚Western‘ diets can reprogram maternal bodily metabolism with maternal nutrient supply precipitating the body-wide imprinting of molecular and cellular adaptations at the level of long-range…

Released at: 16.07.2020, written by webmaster_popp