Chronic ethanol ingestion-induced changes in open-field behavior and oxidative stress in the rat

Pharmacology, biochemistry, and behavior

The effects of chronic ethanol intoxication on the open-field behavior, on antioxidant enzyme activities, and the degree of lipid peroxidation were investigated. Rats consuming a liquid diet containing 7% ethanol for 4, 7, 14, or 21 days exhibited a significantly decreased ambulation activity, accompanied by a reduced frequency and duration of explorative rearing in an open-field task 4, 7, and 14 days after chronic ethanol ingestion, whereas presumed adaptation to the neurologic effects of…

Released at: 05.08.2020, written by webmaster_popp