Projects

Medical Neuroscience Cluster

Genetic determinants of treatment resistant depression

Department of Psychiatry and Psychotherapy and Department of Molecular Neurosciences Medical University of Vienna Prof. Dr. Rupert Lanzenberger and Prof. Dr. Siegfried Kasper Prof. Dr. Tibor Harkany and Mr. Evgenii O. Tretiakov Abstract Treatment-resistant depression (TRD) is a significant clinical problem because of the longevity, severity and prevalence of this subtype of depression, with no […]

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ERC

„Life-long cross-generational priming of the hypothalamus for obesity“ (FOODFORLIFE)

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FWF

The effects of THC on the developing postnatal hippocampus

The effects of THC on the developing postnatal hippocampus Cannabis has recently gained attention in the public’s political debate due to its medical potential, legalization and new ways of consumption. While cannabis use in adults is considered to be safe, new clinical reports are published on its toxicity and its involvement in newly described diseases, […]

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FWF

Cellular diversity in the developing hypothalamus

Cellular diversity in the developing hypothalamus The mammalian hypothalamus exhibits the undoubtedly largest heterogeneity of neurons in the brain. The diversity of hypothalamic neurons is tailored to their multimodal functions, interfacing the periphery and the nervous system. Therefore, some hundred-to-thousand neurons (Romanov et al., 2017) and their interplay with neighboring glia can drive fundamental neuroendocrine […]

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ERC

Secret-Cells

The ERC Advanced Grant project SECRET-CELLS explores cellular diversity and stress-induced cell-state switches in the mammalian hypothalamus. The hypothalamus of the mammalian brain is an essential interface that decodes metabolic challenges through its fast-responding and functionally diverse neuronal populations. Hypothalamic neurons represent output stations under tight central regulation that, through their production of neuropeptides and […]

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