GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome
Brain structure & function
Brain structure & function
The function, regulation and cellular distribution of GABA(A) receptor subunits have been extensively documented in the adult rodent brain and are linked to numerous neurological disorders. However, there is a surprising lack of knowledge on the cellular (sub-) distribution of GABA(A) receptor subunits and of their expressional regulation in developing healthy and diseased foetal human brains. To propose a role for GABA(A) receptor subunits in neurodevelopmental disorders, we studied the…
Released at: 22.09.2020, written by webmaster_popp
